INFLAMMATION

INFLAMMATION

Inflammation is a complex mechanism gathering a number of cell response pathways to harmful stimuli, and can be either acute (initial response of the organism) or chronic (when the response is prolonged). Sustained inflammatory abnormalities are involved in a variety of disorders thereby making inflammatory pathways molecules attractive targets for drug discovery.

CELLULAR MODELS

CELLULAR MODELS

ANALYSIS IN BLOOD SAMPLES

ANALYSIS IN BLOOD SAMPLES

INFLAMMATION ASSAYS

INFLAMMATION ASSAYS

IMMUNOLOGY  , CELL SUBSETS IMMUNOPHENOTYPING & IMMUNE CELL RESPONSE 

Immunophenotyping
(Immune cell subpopulation determination)
Multiple cellular models
fresh biological samples
PF 5.6
NEW ! Multiplexed analysis of protein release Mouse PF 5.8

IL-1β release

Multiple cellular models PF 5.3

TNFα release

Multiple cellular models PF 5.4

IL-6 release

Multiple cellular models PF 5.5

CELL PHYSIOLOGY AND METABOLISM

Cell Migration
(Transwell chamber-based)

Multiple cellular models PF 3.14

Autophagy (LC3B)

Multiple cellular models PF 3.17

Cell proliferation

Multiple cellular models PF 3.9

Lipid peroxidation

Multiple cellular models PF 3.18

Cytolysis

Multiple cellular models PF 3.4

Mitochondrial membrane potential

Multiple cellular models PF 3.3

Caspase 3/7 activation

Multiple cellular models PF 3.2

Caspase 1 activation

Multiple cellular models PF 5.2

CELL SIGNALING

NF κB activation/p65 phosphorylation

Multiple cellular models PF 3.23

ERK activation (pERK1/2)

Multiple cellular models PF 3.27

Calcium signaling

Multiple cellular models PF 3.33

STAT1 translocation

Multiple cellular models PF 3.36

STAT2 translocation

Multiple cellular models PF 3.35

STAT3 translocation

Multiple cellular models PF 3.30

STAT6 phosphorylation

Multiple cellular models PF 3.34

c-Jun phosphorylation

Multiple cellular models PF 3.45

NEW Capacitative calcium entry

HEK293 cell line PF 5.7

Poly-Ubiquitin detection

Multiple cellular models PF 3.38

Histone H2AX phosphorylation

Multiple cellular models PF 5.1

ADDITIONAL CAPABILITIES