IN VITRO TESTING OF NATURAL PRODUCTS & NUTRACEUTICALS

IN VITRO TESTING OF NATURAL PRODUCTS & NUTRACEUTICALS

Fluofarma offers to test natural products in live cells to support the development of new products in investigating a wide range of potential benefits on human health and providing an early prediction potential of toxic effects.

Our panel of cell-based assays enables to test new ingredients, functional food components, nutraceuticals products or dietary supplements for a large array of potential health benefits, to support product health claims.

To support product proof-of-concept, we also offer to demonstrate the mechanism of action of active ingredients.

IN VITRO ASSESSEMENT OF POTENTIAL HEALTH BENEFITS

> Antioxidant activity testing:  anti-aging, sun protective effects

> Metabolic activity testing: including slimming effects

> Protective activity testing: anti-inflammatory effects, anti-cancer activity, protective activity against neurodegenerative diseases and cardio-metabolic disorders.

ADDITIONAL SERVICES TO SUPPORT PRODUCT PROOF-OF-CONCEPT STUDIES

> In vitro toxicity testing: early assessment of the toxicity profile of active ingredients in live cells, including cytotoxicity, genotoxicity, hepatotoxicity, neurotoxicity, cardiotoxicity, ...

> In vitro mechanism of action studies to demonstrate how bioactive food or cosmetic ingredients interfere with intracellular signaling pathways to produce their effect.

> Automated tissue analysis: we offer to demonstrate the molecular underpinning of in vivo effects through the quantitative analysis of key biomarkers in blood or tissue samples retrieved from in vivo experiments.

FLUOFARMA'S ADDED-VALUE

> A 360° project evaluation: your project is audited by a dedicated PhD, who defines with your team the scientific strategy that best meets your goal, budget and time constraints.

> Predictive cellular models, derived from primary cells, cell lines or stem cells, are selected for their ability to recapitulate specific features found in human physiology.

> Automated technologies: to reduce operational costs, shorten lead times and deliver reproducible data, we perform high-throughput cell-based assays in 96-/384-well plates using automated high-content analysis technologies.

> Maximum information: Image and data analysis software applications allow us to quantify morphological and molecular events induced by active compounds in individual cells. Multi-parameter analyses can thus be performed to unravel subtle or hidden ingredient effects.

> Operational results: final reports, which include raw data and interpreted results, are systematically discussed with clients to support their decision-making.