CELL LINE PANEL

Fluofarma routinely uses cell lines in the context of large-scale screens, taking advantage from their fast and uniform growth. In fact, immortalized cell lines, which can be cultured indefinitely in vitro, tend to shorten lead-time to screening and minimize operational costs, while generating highly reproducible results.

OUR EXPERTISE IN CELL LINE CULTURE

> 2D, polarized, or 3D (spheroid) cell cultures in microplates

> Mono- or multi-cell type cultures (using cell lines, primary cells and stem cells)

> Standard cell differentiation procedures (to induce specific phenotypic features or specialized functions)

> Development of in vitro disease models: pharmacologically or genetically generated

OUR PANEL OF CELL LINES

Fluofarma routinely uses over 80 human and animal cell lines. Our panel is continuously complemented with commercial cell lines to meet specific clients’ needs. It currently includes:

> Cancer cell lines derived from human and animal tumors

> Normal immortalized cell lines

> Cell lines expressing our proprietary specific DAP biosensors to quantify y-secretase, calpain or caspase activity

Mitochondrial membrane anchored Bicolor Caspase 3 biosensor showing Caspase 3 activation following FasL treatment (HeLa cells). When Caspase 3 cleaves its target domain, the green fluorescent part is released in the cytosol while the red fluorescent part remains anchored.

INDICATIVE LIST OF CELL LINES

  • LEUKEMIA CELL LINES
Acute T cell leukemia, Acute lymphoblastic leukemia, Monocyte leukemia, Promyelocytic leukemia.
  • SOLID TUMOR CELL LINES
Bladder carcinoma, Breast carcinoma, Cervical adenocarcinoma, Colorectal carcinoma, Fibrosarcoma, Glioblastoma, Hepatoma Kidney, Lung carcinoma, Lymphoma, Melanoma, Neuroblastoma, Pancreas carcinoma, Pheochromocytoma, Pituitary tumor, Prostate carcinoma
  • NORMAL CELL LINES
Adipose tissue, Cornea, Dermis, Epidermis, Kidney, Immune system, Mammary gland, Muscle, Retina.

>>> Please contact us if you want us to perform high-content analysis in a specific cell line, we are continually augmenting our panel.