Anticancer profiling: DCffer® method

Methods

This innovative method compares your drugs to a proprietary functional signature database of reference anti-cancer compounds.

Step 1: Testing of your drug against one selected human cancer cell line by simultaneously detecting 3 key parameters: proliferation inhibition, apoptosis and cytolysis.

Step 2: Determination of a unique signature integrating potency and efficacy at different time points for each parameter.

Step 3: Profiling of your drug comparing its signature with a database of reference anticancer compounds by cluster analysis.

Illustration of DCffer® method

DCffer® method shows that the compound X has an innovative mechanism of action whereas compounds Y and Z are respectively closed from Cisplatin and Docetaxel mechanisms of action.