Predictive toxicity

Predictive toxicity services

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Optimize and secure your drug development

One of the major reasons for drug discovery attrition rate, drugs late stage failures and withdrawals, is an unforeseen in vivo toxicity.
To bypass those problems and optimize and secure your drug development, Fluofarma offers novel High Content Screening tests predictive of toxicity effects.

Innovative read outs of toxicity

Fluofarma has developed a wide range of innovative assays dedicated to assess cytotoxicity, hepatotoxicity, cardiotoxicity and neurotoxicity such as MDR pump function, phospholipidosis, mitochondrial functions, steatosis, micronuclei analysis, etc…

Increase the prediction with relevant cellular models

Moreover to reach the highest level of prediction since the earliest stage of drug development process, those endpoints have been optimized for the most relevant cellular model by using human and rat primary hepatocytes but also 3D hepatocytes cell cultures.

Services for toxicity testing

Our predictive technology can be used to test toxicity at an early stage in a drug's development and enables pharmaceutical companies to obtain their compounds' toxicological profiles using a single method.